Radiation therapy trial for those with DCIS
Women who have ductal carcinoma in situ (DCIS) of the breast are invited to take part in a research study to see whether improvements can be made to radiation treatment.
Participants will have had surgery to remove part of the breast that has DCIS. Radiation treatment after surgery improves the chances of not developing further cancer in that breast. This treatment is suitable for women with DCIS.
In this study, the participants will be assigned to any one of four treatments by a process of randomisation (i.e. treatment will be selected by chance). Neither the participant nor their doctor will be able to select the treatment.
The purpose of this study is to look for better ways to treat people with DCIS. In this research project the researchers will test two aspects of radiation treatment for DCIS.
The researchers will test whether an additional dose of radiation called a boost given to the part of the breast that had the DCIS improves the chances of not having the cancer come back.
One half of the women will be randomly assigned to receive a boost.
A total of 610 participants will participate in the study across centres in New Zealand and Australia. The research project is being organised by the Trans Tasman Radiation Oncology Group.
The study treatment arms are as follows:
- 25 radiation treatments with no boost (extra radiation treatment)
- 25 treatments to the breast, plus 8 boost treatments (a total of 33 treatments)
- 16 treatments with no boost
- 16 treatments to the breast, plus 8 boost treatments(a total of 24 treatments)
This trial is now closed and in follow-up. For further information visit: www.trog.com.au
This study was being run at Waikato Hospital, Christchurch Hospital and Auckland City Hospital.